Institute of Multi-Organ Transplant

Research

The Multi-Organ Transplant Institute has two main challenges in transplantation - tolerance and organ availability. By bringing together both challenges under one roof, the institute comes up with an array of transplant research programs and a long track record of large scale clinical trials for new therapies.

This research theme includes studies directed at optimizing organ and tissue use from human cadaveric donors, as well as aims focusing on the definition of complementary sources for human transplantation. In the first aim, the research team tries to decipher the mechanisms that lead to functional impairment of human organs after donor death, organ harvesting and preservation, and inflammation in the immediate post-transplant period. In the second aim, the team defines complementary sources of transplantable tissues/organs derived from stem cells or non-human donors.